Endpoint Outcomes is pleased to welcome Ian Clarkson as a new research associate to our Boston office:
Prior to joining Endpoint Outcomes, Ian spent a year with AmeriCorps as a Site Coordinator for Reading Partners in Baltimore, Maryland. Ian holds a Bachelor of Arts with honors in Music and concentrations in Chemistry and Mathematical Methods from Bates College in Lewiston, Maine.
A manuscript co-authored by Chris Evans and Brooke Witherspoon reports on the preferences for use and design of electronic patient-reported outcomes in COPD. The results were recently published: Dumais KM, Dias N, Khurana L, Gary ST, Witherspoon B, Evans CJ, Dallabrida SM. Preferences for use and design of electronic patient‑reported outcomes in patients with chronic obstructive pulmonary disease. Patient (2019). https://doi.org/10.1007/s40271-019-00376-9.
Endpoint Outcomes is pleased to welcome Flora Chang as a new research associate to our Long Beach office:
Flora is responsible for collecting, coding and analyzing patient-level data for the development and validation of patient, clinician or observer reported outcomes. Prior to joining Endpoint Outcomes, Flora interned at Alacrita Consulting in London and at Keratin Biosciences in North Carolina. Additionally, Flora worked at Wake Forest Baptist Medical Center in a stress reduction clinical study for patients with migraines. Flora holds a Bachelor of Arts degree in Psychology from Wake Forest University.
Endpoint Outcomes is pleased to welcome Adriana Estrada as a new research coordinator to our Long Beach office:
Adriana is responsible for coordinating patient recruitment activities across all studies, including liaising with patients and physicians to manage consent, screening, enrollment and other related activities. She is also responsible for managing IRB submissions and approvals across all studies. Additionally, Adriana supports other project and research related activities, such as quality checking documents. Adriana has undergraduate research experience in health disparities among Latinos. Adriana holds a Bachelor of Science in Public Health from University of California, San Diego.
Shayna Egan, Siobhan McDonold, Caitlin Pohl and Chris Evans will be presenting posters at the ISPOR meeting in New Orleans in May. For this ISPOR we decided to share some methodological work we have been conducting in the areas of concept elicitation with pediatric subjects and the effect placebo response may have on patient-reported outcome measures. The topics presented are:
- Development of Illustrations to Facilitate Concept Elicitation Interviews with Pediatric Participants
- The role of treatment expectancy on the placebo response as it pertains to the development and implementation of patient-reported outcome measures
The Long Beach and Boston offices came together for a week long retreat to discuss current developments and methodological issues in our field. The topics we covered included: presenting psychometric results, systematic and pragmatic literature reviews, exit interviews, scoring in psychometric studies, current COA issues with the FDA, ensuring consistency across PROs, conceptual equivalency studies and user experience/user interface and usability testing. The retreat was held in Red Rocks area of Las Vegas and the team enjoyed time hiking in the desert and hanging out on the Las Vegas strip.
For team members that would rather exercise their brains than hang out at a hotel pool, an afternoon was spent at Escapology in Las Vegas. Fortunately, they broke out and are available to continue work on your outcomes research studies.
Endpoint Outcomes is pleased to welcome a new senior psychometrician to our office in Boston:
Brandon Foster provides psychometric support to project teams at Endpoint Outcomes. His substantive research interests are focused on the application of modern psychometric methods (i.e., IRT) to the analysis of patient-reported outcomes in clinical trials. Prior to joining Endpoint Outcomes, he worked as a psychometrician for the Massachusetts Department of Elementary and Secondary Education and as a research methodologist for a global health and education NGO located in Massachusetts. Brandon has extensive experience working as a either a high-level quantitative support specialist or project lead for a variety of measure development projects. Brandon holds an MA and PhD in Child Study and Human Development from Tufts University, where he received training in education research methods and psychometrics.
A manuscript co-authored by Shayna Egan, Ted Wells and Brooke Witherspoon reports on the significant health-related quality burden associated with pyruvate kinase deficiency (PKD). Patient interviews were conducted in the US, the Netherlands and Germany to estimate how hemolytic anemia affects patients’ daily lives. The results were recently published: Grace RF, Cohen J, Egan S, Wells T, Witherspoon B, Ryan A, Salek SS, Bodie S, Klassen RJ. The burden of disease in pyruvate kinase deficiency: patients’ perception of the impact on health-related quality of life. Eur J Haematol 2018; 101(6): 758-765. doi: 10.1111/ejh.13128
A manuscript co-authored by Dave Andrae reports on the significant improvements in HRQOL observed in Irritable Bowel Syndrome with diarrhea when treated with eluxadoline. The results were recently published: Abel, JL, Carson RT, Andrae DA. Qual Life Res (2018). https://doi.org/10.1007/s11136-018-2008-z