News

What is happening in the Endpoint Outcomes world.

 

Welcome to Endpoint Outcomes

Endpoint Outcomes is pleased to welcome Adrian Jewett to our Long Beach office. As a Senior Research Associate, Adrian will support the psychometrics and statistics team. Prior to Endpoint Outcomes, Adrian worked at the Claremont Evaluation Center, where he helped to manage and analyze educational evaluative data regarding curriculum impact on student outcomes. His research interests lie primarily in the application of factor analysis, structural equation models, and robust estimation. Adrian holds a Bachelor of Arts degree in Honors Psychology from California State University, Northridge, and a Master of Arts degree in Organizational Behavior & Evaluation from Claremont Graduate University.

Welcome to Endpoint Outcomes

Endpoint Outcomes is please to welcome two new team members to our Boston office: Megha Kamra as a Project Manager and Kathy Vong as a Research Associate.

Prior to Endpoint Outcomes, Megha worked in hospital operations for a digital healthcare startup and hospital administration at a breast cancer center. She also worked in the retail industry as a Project Manager in product content strategy. Megha graduated from Boston University with an MBA and Master in Public Health and completed her undergraduate education in Public Health from Rutgers University.

Prior to Endpoint Outcomes, Kathy interned at The Fenway Institute where she worked alongside the behavioral health sciences team to study the feasibility and acceptability of a digital HIV pre-exposure prophylaxis pill to monitor medication adherence in high-risk populations. Additionally, Kathy has worked as a research assistant in a mental health lab dedicated to developing digital interventions for individuals with severe mental illness. Kathy holds a Bachelor of Arts degree in Biology with a minor in Public Health from Boston University.

Happy Hour Revised

The COVID-19 pandemic has changed the way we all work, but it is good to know we can still take a break to have a virtual happy hour with some of the team members in Boston.

The Burden of Kabuki Syndrome

A manuscript co-authored by Shayna Egan, Maggie Paulich and Chris Evans reports on the significant health-related quality of life burden associated with Kabuki Syndrome.  The results were recently published: Theodore-Oklota C, Egan S, Paulich M, Evans CJ, Hartman DS, Hoffman DL, Bjornsson HT.  Caregiver-reported clinical characteristics and the burden associated with Kabuki syndrome.  Am J Med Genet 2020;1-9.

Development of PRO Measures in a Rare Disease

A manuscript co-authored by Shayna Egan, Ted Wells and Chris Evans documents to qualitative research conducted to develop two new PRO measures to assess symptoms and impacts in Pyruvate Kinase Deficiency.  The results were recently published: Salek S, Boscoe AN, Piantedosi S, Egan S, Evans CJ, Wells T, Cohen J, Klassen RJ, Grace R, Storm M.  Development of the Pyruvate Kinase Deficiency Diary (PKDD) and Pyruvate Kinase Deficiency Impact Assessment (PKDIA): Disease-Specific Assessments. Eur J Haematol. 2020; 104: 427-434.

ISPOR “Virtual” Presentations

Despite a virtual conference due to COVID-19, the following research by Endpoint Outcomes and its clients will be published on the conference website.

  • Development of a Pediatric Faces Scale for use in Multiple Disease Areas
  • The Humanistic Burden of Glycogen Storage Disease Type Ia: The Impact on Symptoms, Diet, and Health-related Quality of Life
  • Development of Conceptual Frameworks and Pilot PRO Measures in OTC Deficiency
  • Development of Illustrations for Use in Pediatric Qualitative Interviews
  • Itch Reported Outcome Tool For Caregivers Of Pediatric Patients With Cholestatic Liver Disease: An Analysis Of Validation And Scoring From The ICONIC Maralixibat Study
  • A descriptive framework for understanding patterns of in intensive longitudinal patient diaries

New White Paper

Quantitative researchers at Endpoint Outcomes overview some of the history that underpins the scoring approaches that are used in clinical outcome assessments in a new white paper.

Highlights include:

    1. The contributions to instrument scoring from the fields of psychophysics, intelligence testing, scaling, attitude measurement, and classical and modern test theories
    2. The use of scoring approaches in medical research and a brief introduction into the mathematics that constitute scoring
    3. Potential consequences of different approaches to scoring

The white paper can be downloaded here and correspondence can be directed to: dave.andrae@endpointoutcomes.com

Welcome to Endpoint Outcomes

Endpoint Outcomes is pleased to welcome a new senior research associate, Elliott Blatt, to our Boston office:

Prior to joining Endpoint Outcomes, Elliott worked at The Fenway Institute helping conduct a health needs assessment for transgender and non-binary populations. Elliott holds a Bachelor of Science degree in Biological Sciences from Wayne State University as well as a Masters in Public Health degree from Boston University.

You Cannot Keep Endpoint Outcomes Locked Up

Boston team members proved yet again, there isn’t an escape room that can hold them. Sadly, the same never seems to be true of the Long Beach office.  Clients are encouraged to contact the Boston office in the first instance to secure the most intelligent team members for their projects.

ISOQOL Presentations

Endpoint Outcomes will be presenting at the International Society for Quality of Life Research 26th Annual Conference in San Diego, California on October 20-23, 2019. Dave Andrae will be presenting on “Scoring methods: History, practices, and pragmatic implications for different options”. Martha Gauthier and Nate Johnson will be presenting on “Identification and recommendations of readability tests for the evaluation of clinical outcome assessments (COAs)”.