A manuscript co-authored by Shayna Egan, Ted Wells and Brooke Witherspoon reports on the significant health-related quality burden associated with pyruvate kinase deficiency (PKD). Patient interviews were conducted in the US, the Netherlands and Germany to estimate how hemolytic anemia affects patients’ daily lives. The results were recently published:   Grace RF, Cohen J, Egan S, Wells T, Witherspoon B, Ryan A, Salek SS, Bodie S, Klassen RJ. The burden of disease in pyruvate kinase deficiency: patients’ perception of the impact on health-related quality of life.  Eur J Haematol 2018; 101(6): 758-765. doi: 10.1111/ejh.13128