In 2018, researchers at Endpoint Outcomes embarked on an exercise to develop illustrations to assist pediatric research participants in communicating their disease experience to our interviewers.  A list of concepts commonly found in pediatric diseases was developed based on a review of generic pediatric health-related quality of life measures.  Draft illustrations were initially developed by a professional illustrator to reflect the core concepts.  The draft illustrations were then reviewed by staff at Endpoint Outcomes to ensure they reflect the relevant concepts and illustrations were subsequently altered if necessary. The illustrations have been developed to be gender and ethnicity/race neutral and to focus on disease deficits.  Currently, the illustrations are being pilot tested in two pediatric studies in rare diseases. A formal evaluation of the content validity of the measures is planned for later in the year. For additional information on this work please contact Shayna Egan: Shayna.egan@endpointoutcomes.com